APRECAP 125/80MG

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What is APRECAP 125/80MG?

APRECAP 125/80MG is a prescription medication that contains Aprepitant as its active ingredient, available in two dosage strengths: 125 mg and 80 mg. It belongs to a class of drugs known as neurokinin-1 (NK1) receptor antagonists. This medication is typically used in combination with other antiemetic agents to prevent nausea and vomiting caused by chemotherapy or, in some cases, after surgery.

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What is the Use of APRECAP 125/80MG?

APRECAP 125/80MG is primarily used for:

• Prevention of chemotherapy-induced nausea and vomiting (CINV): It is especially effective for delayed-phase CINV, which occurs 24 hours or more after chemotherapy.

• Prevention of postoperative nausea and vomiting (PONV) in certain patients.

• It is used in combination with other medications such as corticosteroids (e.g., dexamethasone) and 5-HT3 antagonists (e.g., ondansetron) for maximum effectiveness.

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Benefits of APRECAP 125/80MG

• Effective prevention of nausea and vomiting, especially in patients undergoing highly emetogenic chemotherapy.

• Improves patient comfort and quality of life during cancer treatment by reducing the risk of vomiting.

• Convenient oral dosing makes it easy to administer as part of an antiemetic regimen.

• Prolonged action helps manage both acute and delayed phases of CINV.

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Dosage and Administration

• The usual dosage involves one 125 mg capsule taken orally on Day 1 (an hour before chemotherapy), followed by one 80 mg capsule on Days 2 and 3.

• Always use APRECAP under the supervision of a healthcare professional, and strictly follow the prescribed regimen.

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Side Effects of APRECAP 125/80MG

Like all medications, APRECAP can cause side effects, although not everyone experiences them. Common side effects include:

• Fatigue or tiredness

• Constipation or diarrhea

• Loss of appetite

• Hiccups

• Headache

• Dizziness

• Indigestion or acid reflux

Serious but rare side effects:

• Hypersensitivity reactions such as rash, itching, or swelling

• Severe liver issues (indicated by yellowing of the skin or eyes, dark urine)

• Allergic reactions including difficulty breathing

Contact your doctor immediately if you notice any severe or persistent side effects.

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Precautions and Warnings

• Inform your doctor about any liver problems, pregnancy, or breastfeeding status.

• APRECAP may interact with certain medications, including warfarin, oral contraceptives, and certain chemotherapy drugs. Always share a full list of your medications with your healthcare provider.

• Not recommended for use in children unless specifically prescribed by a physician.

• What is APRECAP 125/80MG used for?
  APRECAP is used to prevent nausea and vomiting caused by chemotherapy, particularly highly or moderately emetogenic cancer treatments.

• How does APRECAP 125/80MG work?
  It works by blocking neurokinin-1 (NK1) receptors in the brain, which are involved in triggering nausea and vomiting.

• When should I take APRECAP 125/80MG?
  Typically, you take 125 mg one hour before chemotherapy on Day 1, followed by 80 mg on Days 2 and 3. Follow your doctor’s exact instructions.

• Can APRECAP be taken alone to prevent nausea and vomiting?
  No, it is usually taken with a corticosteroid (like dexamethasone) and a 5-HT3 antagonist (like ondansetron) for maximum effectiveness.

• Is APRECAP 125/80MG safe for long-term use?
  APRECAP is intended for short-term use in chemotherapy cycles. Long-term use is not typical and should be evaluated by a healthcare professional.

• What are the side effects of APRECAP 125/80MG?
  Common side effects include fatigue, hiccups, constipation, loss of appetite, and headache. Serious side effects are rare but may include allergic reactions or liver issues.

• Can APRECAP 125/80MG be taken with food?
  Yes, it can be taken with or without food, unless otherwise directed by your healthcare provider.

• What should I do if I miss a dose?
  Contact your doctor or pharmacist immediately. Do not double up on the next dose unless advised by a healthcare professional.

• Is APRECAP safe during pregnancy or breastfeeding?
  It should only be used during pregnancy or breastfeeding if clearly needed and prescribed by a doctor.

• Does APRECAP interact with other medications?
  Yes, it can interact with medications such as warfarin, hormonal contraceptives, certain antifungals, and antidepressants. Always inform your doctor about all medications you’re taking.

• Can APRECAP affect birth control effectiveness?
  Yes, it may reduce the effectiveness of hormonal contraceptives. Use an alternative or backup method during treatment and for 28 days afterward.

• Is APRECAP 125/80MG a chemotherapy drug?
  No, APRECAP is not chemotherapy. It is an antiemetic used to prevent chemotherapy-induced nausea and vomiting.

• Is a prescription required for APRECAP 125/80MG?
  Yes, it is a prescription-only medication and should be used under medical supervision.

• Can elderly patients take APRECAP 125/80MG?
  Yes, but they should be monitored closely as they may be more sensitive to side effects.

• Where should I store APRECAP 125/80MG?
  Store it at room temperature, away from moisture and heat. Keep it out of reach of children.