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Isosorbide Mononitrate Extended-Release Tablets

Product Name: Isosorbide Mononitrate Extended-Release Tablets
Salt Name: Isosorbide Mononitrate
Strength: 30 mg / 60 mg / 120 mg (available strengths may vary)
Manufacturer: [Manufacturer name varies by brand; examples include Sun Pharma, Zydus, Lupin, Torrent, etc.]
Storage: Store below 25°C (77°F), in a dry place. Protect from light and moisture. Keep out of reach of children.
Presentation: Blister pack or bottle pack of 10, 30, or 100 extended-release tablets (depending on brand and market)

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What is Isosorbide Mononitrate Extended-Release Tablets?

Isosorbide Mononitrate Extended-Release Tablet is a prescription medication that belongs to a class of drugs called nitrates. It is designed to be slowly released in the body over time to provide a long-lasting effect. This medication works by relaxing and widening blood vessels, making it easier for blood to flow through the heart and reducing the heart’s workload.


What is the Use of Isosorbide Mononitrate Extended-Release Tablets?

The primary use of Isosorbide Mononitrate ER Tablets is to prevent chest pain (angina) in people with coronary artery disease. It is not intended to stop chest pain once it occurs, but rather to reduce the frequency and severity of angina attacks.

It may also be prescribed for:

  • Chronic heart failure (as part of combination therapy)

  • Off-label uses, as determined by your healthcare provider


Benefits of Isosorbide Mononitrate Extended-Release Tablets

  • Prevents angina attacks by improving blood and oxygen supply to the heart

  • Long-acting formula provides relief throughout the day with once-daily dosing

  • Reduces frequency and severity of chest pain

  • Improves exercise tolerance in people with heart disease

  • ✅ Helps in managing symptoms of heart failure (when combined with other medications)


How to Use Isosorbide Mononitrate Extended-Release Tablets

  • Take the tablet once daily, usually in the morning.

  • Swallow whole with water; do not crush or chew.

  • Take at the same time each day for best results.

  • Follow your doctor’s instructions precisely; do not change your dose without medical advice.


Possible Side Effects of Isosorbide Mononitrate Extended-Release Tablet

Like all medications, this drug may cause side effects. Most are mild and improve over time.

Common side effects:

  • Headache (most common, often decreases with continued use)

  • Dizziness or lightheadedness

  • Flushing (warmth, redness)

  • Nausea

Serious side effects (seek medical help immediately):

  • Fainting

  • Irregular heartbeat

  • Severe hypotension (low blood pressure)

  • Shortness of breath

  • Allergic reactions (rash, itching, swelling)

⚠️ Important: Do not use this medication with erectile dysfunction drugs (like sildenafil, tadalafil, or vardenafil), as it may cause a severe drop in blood pressure.


Precautions Before Using Isosorbide Mononitrate Extended-Release Tablets

  • Inform your doctor about any heart conditions, liver problems, or history of stroke.

  • Avoid alcohol, as it may increase the risk of side effects like dizziness or fainting.

  • Do not stop this medication suddenly; consult your doctor first.


Storage Instructions

  • Store at room temperature, away from moisture, heat, and direct sunlight.

  • Keep out of reach of children and pets.

What is Isosorbide Mononitrate Extended-Release used for?
It is primarily used to prevent chest pain (angina) caused by heart disease. It may also be used in heart failure management as prescribed.


2. How does Isosorbide Mononitrate work?
It works by relaxing and widening blood vessels, improving blood flow to the heart and reducing its workload.


3. Can I use it to stop a chest pain episode that’s already started?
No. It is not intended for acute relief of angina attacks. Fast-acting nitrates like nitroglycerin are used for that purpose.


4. How should I take Isosorbide Mononitrate Extended-Release Tablets?
Take it once daily, usually in the morning, with or without food. Swallow the tablet whole—do not crush or chew.


5. What are the common side effects?

  • Headache

  • Dizziness or lightheadedness

  • Flushing

  • Nausea
    These often improve with continued use.


6. What should I do if I miss a dose?
Take the missed dose as soon as you remember, unless it’s almost time for your next dose. Do not double up.


7. Can I drink alcohol while taking this medication?
Avoid alcohol, as it can increase the risk of side effects like dizziness and fainting.


8. Is it safe during pregnancy or breastfeeding?
Use only if clearly prescribed by your doctor. Discuss risks and benefits before use if you are pregnant or breastfeeding.


9. Can I drive or operate machinery while on this medicine?
Avoid driving if you feel dizzy or lightheaded after taking the medication, especially when you first start it.


10. Can I stop taking it suddenly?
No. Sudden discontinuation can cause rebound angina. Always consult your doctor before stopping.


11. Can I take erectile dysfunction drugs (like Viagra) with this medicine?
Absolutely not. Combining the two can lead to a dangerous drop in blood pressure.


12. What should I tell my doctor before starting this medication?
Inform your doctor if you have:

  • Low blood pressure

  • Liver or kidney disease

  • Recent stroke or heart attack

  • Allergies to nitrates


13. How long does it take to start working?
The extended-release form provides gradual relief, and it may take a few days to see full benefits in angina prevention.


14. How do I store Isosorbide Mononitrate Extended-Release Tablets?
Store at room temperature, away from moisture and heat. Keep in the original container and out of reach of children.


15. Is this medication habit-forming or addictive?
No. Isosorbide Mononitrate is not addictive, but must be taken regularly for best results.

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