HERMAB 440MG

Product Name: HERMAB 440MG Injection
Salt Name: Trastuzumab
Strength: 440 mg
Manufacturer: Hetero Healthcare Ltd.
Storage: Store at 2°C – 8°C (Refrigerated). Do not freeze or shake.
Presentation: Single-use vial for intravenous infusion.

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What is HERMAB 440MG?

HERMAB 440MG is an anti-cancer medication containing Trastuzumab as its active ingredient. It is a monoclonal antibody that targets the HER2 (human epidermal growth factor receptor 2) protein, which is overexpressed in certain types of breast and stomach cancers. By blocking this protein, HERMAB 440MG helps inhibit the growth of cancer cells and prevents their spread.

This injection is administered intravenously (IV) under the supervision of an oncologist or qualified healthcare professional.


What is the Use of HERMAB 440MG?

HERMAB 440MG is primarily used for the treatment of HER2-positive cancers, including:

  • Breast Cancer: Both early-stage and metastatic HER2-positive breast cancer in women and men.

  • Gastric (Stomach) Cancer: For patients with HER2-positive advanced gastric or gastroesophageal junction adenocarcinoma.

It may be prescribed alone or in combination with other chemotherapy medicines, depending on the treatment plan.


Benefits of HERMAB 440MG

  • Targeted Therapy: Specifically attacks HER2-positive cancer cells, minimizing harm to normal cells.

  • Improved Survival Rate: Shown to significantly improve overall survival and disease-free survival in breast and gastric cancer patients.

  • Reduces Cancer Progression: Slows or stops the growth and spread of tumors.

  • Combination Flexibility: Works effectively with other chemotherapy agents for enhanced outcomes.


How HERMAB 440MG Works

HERMAB 440MG (Trastuzumab) binds to the HER2 receptor on cancer cells, blocking signals that trigger cell growth and division. It also activates the body’s immune system to attack and destroy these cancerous cells.


Side Effects of HERMAB 440MG

Like all medications, HERMAB 440MG may cause some side effects. Common and serious ones include:

Common Side Effects:

  • Fever, chills

  • Nausea, vomiting

  • Diarrhea

  • Headache

  • Fatigue or weakness

  • Rash or itching

  • Muscle or joint pain

Serious Side Effects (require medical attention):

  • Heart-related issues such as heart failure or irregular heartbeat

  • Severe allergic reactions (breathing difficulty, swelling, rash)

  • Lung problems (shortness of breath, cough)

  • Liver enzyme elevation


Precautions & Warnings

  • HERMAB 440MG should only be used under medical supervision.

  • Cardiac function should be monitored before and during treatment.

  • Not recommended for use during pregnancy or breastfeeding unless prescribed by a doctor.

  • Inform your doctor if you have any heart disease, respiratory problems, or prior chemotherapy.


Storage & Administration

  • Store at 2°C–8°C (refrigerated).

  • Do not freeze or shake the vial.

  • The injection is to be prepared and administered by a qualified healthcare professional only.

1. What is HERMAB 440MG used for?

HERMAB 440MG is used to treat HER2-positive breast cancer and HER2-positive gastric (stomach) cancer. It targets cancer cells that overexpress the HER2 protein and helps slow or stop their growth.


2. What is the active ingredient in HERMAB 440MG?

The active ingredient in HERMAB 440MG is Trastuzumab, a monoclonal antibody that specifically binds to the HER2 receptor on cancer cells.


3. How does HERMAB 440MG work?

HERMAB 440MG works by blocking HER2 receptors on cancer cells, preventing them from receiving growth signals. It also activates the body’s immune system to destroy these cells.


4. How is HERMAB 440MG administered?

It is given as an intravenous (IV) infusion by a qualified healthcare professional, usually in a hospital or cancer treatment center.


5. How often should HERMAB 440MG be given?

The dosing schedule varies depending on your treatment plan. It may be administered weekly or every three weeks, as prescribed by your oncologist.


6. Can HERMAB 440MG be used alone?

Yes, it can be used as a single agent or in combination with chemotherapy medicines such as paclitaxel, docetaxel, or cisplatin, depending on the stage and type of cancer.


7. Who should not take HERMAB 440MG?

Patients with severe heart disease, allergy to Trastuzumab, or uncontrolled infections should avoid this medicine unless advised by their doctor.


8. What are the common side effects of HERMAB 440MG?

Common side effects include fever, chills, nausea, fatigue, headache, and diarrhea. These are usually mild and temporary.


9. Are there any serious side effects?

Yes. Serious side effects may include heart problems, allergic reactions, breathing difficulties, or liver issues. Immediate medical help is required if these occur.


10. Can HERMAB 440MG cause heart problems?

Yes, it may affect heart function in some patients. Regular heart monitoring (ECHO or ECG) is recommended before and during treatment.


11. Is HERMAB 440MG safe during pregnancy or breastfeeding?

No. It is not recommended during pregnancy or breastfeeding as it may harm the unborn or nursing baby. Women should use effective contraception during and after treatment.


12. Can HERMAB 440MG be taken with other medicines?

Yes, but only under medical supervision. Your doctor will decide which medicines can be safely used along with HERMAB 440MG.


13. What precautions should be taken while using HERMAB 440MG?

  • Always get the infusion from a qualified medical professional.

  • Monitor heart function regularly.

  • Inform your doctor about all other medicines or supplements you’re taking.

  • Report any breathing problems or chest pain immediately.


14. How should HERMAB 440MG be stored?

It should be stored in a refrigerator between 2°C–8°C. Do not freeze or shake the vial. Keep it out of reach of children.


15. What should I do if I miss a dose?

If you miss a scheduled dose, contact your doctor immediately to reschedule. Do not try to self-administer or double the next dose.

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