What is CANMAB 150MG?
CANMAB 150MG is an anti-cancer (antineoplastic) medication that contains the active ingredient Trastuzumab. It is a monoclonal antibody specifically designed to target the HER2 (human epidermal growth factor receptor 2) protein, which promotes the growth of cancer cells. CANMAB is the biosimilar version of Herceptin® and is manufactured by Biocon Biologics.
What is the use of CANMAB 150MG?
CANMAB 150MG is used in the treatment of HER2-positive cancers, including:
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HER2-positive breast cancer (early and metastatic)
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HER2-positive metastatic gastric cancer
It may be used alone or in combination with chemotherapy such as paclitaxel, docetaxel, or other regimens, depending on the cancer stage and treatment plan.
Benefits of CANMAB 150MG:
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Targeted therapy that specifically attacks HER2-positive cancer cells
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Proven efficacy in reducing tumor size and slowing disease progression
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Improves survival rates and quality of life in HER2-positive breast and gastric cancer patients
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Can be used in neoadjuvant (before surgery), adjuvant (after surgery), or metastatic settings
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A cost-effective biosimilar alternative to innovator trastuzumab brands
Side Effects of CANMAB 150MG:
Like all anticancer drugs, CANMAB can cause side effects. Patients should be monitored closely during therapy.
Common Side Effects:
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Fever, chills during infusion
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Fatigue, weakness
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Nausea, vomiting
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Diarrhea
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Headache
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Rash or skin irritation
Serious Side Effects (require immediate medical attention):
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Heart problems (especially in patients with previous heart disease or those receiving anthracyclines)
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Infusion-related reactions (difficulty breathing, swelling, low blood pressure)
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Liver enzyme elevation
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Low blood cell counts
⚠️ Note: Cardiac function must be monitored during treatment. Dose adjustments or discontinuation may be required in case of cardiotoxicity.
Important Usage Information:
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Administered intravenously under the supervision of a qualified oncologist
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Pre-medications may be given to reduce the risk of infusion reactions
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Not recommended during pregnancy or breastfeeding
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Requires cardiac function tests (e.g., echocardiogram) before and during treatment
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What is CANMAB 150MG used for?
CANMAB 150MG is used to treat HER2-positive breast cancer and metastatic gastric cancer. It is typically used in combination with other chemotherapy drugs. -
What is the active ingredient in CANMAB 150MG?
The active ingredient is Trastuzumab, a monoclonal antibody that targets the HER2 receptor on cancer cells. -
How does CANMAB 150MG work?
It binds to the HER2 receptors on cancer cells and inhibits their growth and survival. It also activates the immune system to destroy these cells. -
Is CANMAB 150MG a chemotherapy drug?
No, it is not traditional chemotherapy. It is a targeted therapy, specifically a monoclonal antibody, used alongside chemotherapy. -
How is CANMAB 150MG administered?
CANMAB 150MG is administered as an intravenous (IV) infusion under the supervision of a healthcare professional. -
How often is CANMAB 150MG given?
It is usually given every week or every 3 weeks, depending on the treatment regimen and patient response. -
Can CANMAB 150MG cause side effects?
Yes. Common side effects include fever, chills, nausea, fatigue, headache, and rash. Serious side effects can include heart problems and allergic reactions. -
Is cardiac monitoring required with CANMAB 150MG?
Yes. Echocardiograms or MUGA scans are recommended regularly to monitor heart function during treatment. -
Is CANMAB 150MG safe during pregnancy?
No. It is not recommended during pregnancy due to the risk of harm to the unborn baby. Effective contraception is advised during and for 7 months after treatment. -
Can CANMAB 150MG be used alone?
In some cases, yes. However, it is often more effective when used in combination with chemotherapy or other targeted therapies. -
What should I do if I miss a dose of CANMAB 150MG?
Contact your doctor immediately. Your healthcare provider will decide when to reschedule the missed dose. -
Are there any special precautions while using CANMAB 150MG?
Yes. Inform your doctor if you have a history of heart disease, are pregnant or breastfeeding, or are taking any other medications. -
How long does treatment with CANMAB 150MG last?
Treatment duration varies but may continue for up to a year or longer, based on response and tolerance. -
Can I take other medications with CANMAB 150MG?
Inform your doctor about all the medications and supplements you’re taking to avoid potential drug interactions. -
Is CANMAB 150MG effective for all types of breast cancer?
No. It is effective only in patients with HER2-positive tumors. HER2 status must be confirmed before starting treatment.
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