What is HIPOLY-B 5LAKH IU?
HIPOLY-B 5 LAKH IU is an antibiotic injection containing Polymyxin B Sulfate as its active ingredient. It belongs to the polymyxin class of antibiotics and is primarily used to treat severe bacterial infections caused by multidrug-resistant (MDR) gram-negative bacteria.
This medicine is administered intravenously (IV) or intramuscularly (IM) under the supervision of a qualified healthcare professional.
What is the Use of HIPOLY-B 5LAKH IU?
HIPOLY-B 5 LAKH IU is prescribed for the treatment of serious infections such as:
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Bloodstream infections (septicemia)
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Meningitis (infection of the brain and spinal cord)
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Urinary tract infections (UTIs)
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Respiratory tract infections (including hospital-acquired pneumonia)
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Wound or skin infections caused by resistant bacteria like Pseudomonas aeruginosa, Acinetobacter baumannii, and Klebsiella pneumoniae
It is often used when other antibiotics have failed to work.
Benefits of HIPOLY-B 5LAKH IU
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Effective against multidrug-resistant bacteria
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Last-resort therapy for life-threatening infections
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Rapid bactericidal action by damaging bacterial cell membranes
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Useful in both systemic and topical infections (as prescribed)
How HIPOLY-B 5LAKH IU Works
Polymyxin B interacts with the outer membrane of gram-negative bacteria, altering its structure and causing leakage of essential cell components. This leads to bacterial cell death, making it highly effective against resistant bacterial strains.
Side Effects of HIPOLY-B 5LAKH IU
Common Side Effects:
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Pain or redness at the injection site
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Dizziness
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Numbness or tingling sensation
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Mild kidney discomfort
Serious Side Effects (seek medical help immediately):
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Nephrotoxicity (kidney damage)
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Neurotoxicity (nerve damage)
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Difficulty breathing or muscle weakness
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Severe allergic reaction
Precautions & Warnings
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Use only under strict medical supervision.
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Monitor kidney and nerve function during treatment.
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Avoid concurrent use with other nephrotoxic or neurotoxic drugs.
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Use cautiously in elderly patients and those with renal impairment.
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Not recommended during pregnancy or breastfeeding unless essential.
Storage & Administration
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Storage: Store below 25°C, protected from light and moisture. Reconstitute as directed before use.
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Administration: Given intravenously (IV) or intramuscularly (IM) by a trained healthcare professional only.
1. What is HIPOLY-B 5 LAKH IU used for?
It is used to treat serious bacterial infections caused by multidrug-resistant gram-negative organisms.
2. What is the active ingredient?
Polymyxin B Sulfate.
3. How is HIPOLY-B administered?
It is given intravenously (IV) or intramuscularly (IM) by a healthcare professional.
4. Can HIPOLY-B be used for mild infections?
No, it is reserved for severe or life-threatening infections when other antibiotics fail.
5. What are the common side effects?
Pain at injection site, dizziness, tingling, and mild kidney issues.
6. Can HIPOLY-B cause kidney problems?
Yes. It can be nephrotoxic, so kidney function must be closely monitored.
7. What are the signs of kidney toxicity?
Reduced urine output, swelling, and fatigue. Contact your doctor immediately if these occur.
8. Can HIPOLY-B cause nerve damage?
In rare cases, yes. Symptoms include numbness, tingling, or muscle weakness.
9. Is HIPOLY-B safe during pregnancy?
Not recommended unless clearly needed and prescribed by a physician.
10. Can HIPOLY-B be given to children?
Yes, but only under strict medical supervision with dose adjustment.
11. What should I do if I miss a dose?
Inform your doctor immediately. Do not self-administer or double the next dose.
12. Can HIPOLY-B interact with other medicines?
Yes, especially with other nephrotoxic drugs (e.g., aminoglycosides, vancomycin). Always inform your doctor.
13. How should HIPOLY-B be stored?
Store below 25°C, in a cool, dry place. Use immediately after reconstitution.
14. Is HIPOLY-B effective against all bacteria?
No, it is effective mainly against gram-negative bacteria like Pseudomonas and Klebsiella.
15. Who manufactures HIPOLY-B 5 LAKH IU?
Hetero Healthcare Ltd., a leading Indian pharmaceutical company.






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