GRASTIM 300MCG (VIAL)

What is GRASTIM 300MCG (VIAL)?

GRASTIM 300MCG is an injectable medication containing Filgrastim 300 mcg. Filgrastim is a recombinant human granulocyte colony-stimulating factor (G-CSF) that stimulates the bone marrow to produce white blood cells (neutrophils).

It is commonly used in patients with chemotherapy-induced neutropenia, bone marrow transplantation, or chronic neutropenia to reduce the risk of infections.

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What is the use of GRASTIM 300MCG (VIAL)?

• To prevent or treat neutropenia caused by chemotherapy.

• To reduce the risk of infections in patients with low white blood cells.

• To mobilize stem cells for collection before hematopoietic stem cell transplantation.

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Benefits of GRASTIM 300MCG (VIAL):

• Increases production of neutrophils to improve immune defense.

• Helps patients tolerate chemotherapy by lowering infection risk.

• Supports faster recovery of white blood cells after chemotherapy.

• Can be used for stem cell mobilization for transplantation.

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Side Effects of GRASTIM 300MCG (VIAL):

• Common side effects:

  • Bone or muscle pain

  • Headache

  • Mild fever or fatigue

  • Injection site reactions (redness, swelling)

• Rare/serious side effects:

  • Splenomegaly or spleen rupture

  • Severe allergic reactions

  • Low platelet count or bleeding disorders

Q1. What is GRASTIM 300MCG (VIAL) used for?
It is used to increase white blood cell count in patients with neutropenia, especially during or after chemotherapy.

Q2. What is the active ingredient in GRASTIM 300MCG (VIAL)?
The active ingredient is Filgrastim 300 mcg, a recombinant human granulocyte colony-stimulating factor (G-CSF).

Q3. How does GRASTIM 300MCG work?
It stimulates the bone marrow to produce more neutrophils, which help fight infections.

Q4. How is GRASTIM 300MCG administered?
It is given subcutaneously (under the skin) or intravenously, typically by a healthcare professional.

Q5. Can GRASTIM 300MCG prevent infections during chemotherapy?
Yes, it reduces the risk of neutropenia-related infections and helps patients tolerate chemotherapy.

Q6. What are the common side effects?
Bone or muscle pain, headache, mild fever, fatigue, and injection site reactions like redness or swelling.

Q7. Are there serious side effects?
Rare but serious effects include splenomegaly, spleen rupture, severe allergic reactions, or low platelet counts.

Q8. Can GRASTIM 300MCG be used for stem cell transplantation?
Yes, it is used to mobilize stem cells for collection prior to hematopoietic stem cell transplantation.

Q9. Can children take GRASTIM 300MCG?
Yes, but dosage must be adjusted according to body weight and medical condition.

Q10. How long does it take to increase white blood cell count?
Typically, neutrophil counts rise within 1–2 days, depending on dosage and patient response.

Q11. Can GRASTIM 300MCG be stored at room temperature?
No. It should be stored at 2–8°C (refrigerated), protected from light, and must not be frozen.

Q12. Can pregnant or breastfeeding women use this injection?
Use only under doctor supervision, as safety during pregnancy or breastfeeding needs assessment.

Q13. Can GRASTIM 300MCG be self-administered at home?
Some patients may be trained, but it should follow medical guidance and proper storage instructions.

Q14. What should I do if I miss a dose?
Contact your doctor for instructions, as timing is critical during chemotherapy schedules.

Q15. Is monitoring required during treatment?
Yes, complete blood counts and spleen monitoring are recommended to ensure safety and effectiveness.