DYRONIB 70

Product Name: DYRONIB 70
Salt Name: Dasatinib
Strength: 70 mg
Manufacturer: Natco Pharma Ltd.
Storage: Store below 25°C in a dry place, protected from light and moisture. Keep out of reach of children.
Presentation: Film-coated tablets, usually supplied in blister packs.

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What is DYRONIB 70?

DYRONIB 70 is a targeted cancer therapy medicine that contains Dasatinib 70 mg as its active ingredient. It belongs to the class of tyrosine kinase inhibitors (TKIs) and works by blocking certain proteins that promote the growth of cancer cells.


What is the use of DYRONIB 70?

  • Used primarily for chronic myeloid leukemia (CML) in adults and children who are Philadelphia chromosome-positive (Ph+).

  • Prescribed for acute lymphoblastic leukemia (ALL) that is Philadelphia chromosome-positive.

  • Effective in patients who are resistant or intolerant to prior therapies like Imatinib.


Benefits of DYRONIB 70:

  • Targets and blocks cancer cell growth at the molecular level.

  • Helps achieve remission in patients with chronic myeloid leukemia and Ph+ ALL.

  • Can be used in patients who have not responded to other treatments.

  • Oral administration makes it convenient compared to intravenous chemotherapy.

  • Improves overall survival and quality of life in certain leukemia patients.


Side Effects of DYRONIB 70:

Like all cancer therapies, DYRONIB 70 may cause side effects:

  • Common side effects:

    • Nausea, vomiting, diarrhea

    • Fatigue, headache

    • Low blood cell counts (anemia, neutropenia, thrombocytopenia)

    • Fluid retention, swelling of hands, feet, or eyes

  • Less common / serious side effects:

    • Liver problems (jaundice, elevated liver enzymes)

    • Heart issues (arrhythmias, heart failure)

    • Severe bleeding

    • Shortness of breath or lung problems

    • Allergic reactions (rash, itching, swelling)

Q1. What is DYRONIB 70 used for?
DYRONIB 70 (Dasatinib 70 mg) is used to treat Philadelphia chromosome-positive chronic myeloid leukemia (Ph+ CML) and Philadelphia chromosome-positive acute lymphoblastic leukemia (Ph+ ALL), especially in patients resistant or intolerant to prior therapies.

Q2. How does DYRONIB 70 work?
It is a tyrosine kinase inhibitor (TKI) that blocks abnormal proteins responsible for cancer cell growth, slowing or stopping the spread of leukemia cells.

Q3. How should DYRONIB 70 be taken?
Take DYRONIB 70 orally, usually once daily, as prescribed by your doctor. Swallow the tablet whole with water, and take it at the same time every day.

Q4. Can DYRONIB 70 be taken with food?
It can be taken with or without food, but avoid grapefruit or grapefruit juice, as it may interfere with the medicine.

Q5. What are the common side effects of DYRONIB 70?
Nausea, vomiting, diarrhea, fatigue, headache, low blood cell counts, and fluid retention (swelling of hands, feet, or eyes).

Q6. What serious side effects should I watch for?
Serious effects may include liver problems, heart issues, severe bleeding, lung problems, or allergic reactions. Contact your doctor immediately if you experience shortness of breath, chest pain, or jaundice.

Q7. Can DYRONIB 70 affect blood counts?
Yes, it may cause low red blood cells, white blood cells, or platelets, increasing the risk of infection, fatigue, or bleeding.

Q8. Is DYRONIB 70 safe during pregnancy or breastfeeding?
No. DYRONIB 70 may harm the unborn baby and is not recommended during pregnancy or breastfeeding. Effective contraception is necessary.

Q9. Can I take other medicines with DYRONIB 70?
Some medicines may interact with Dasatinib (antacids, certain antifungals, anticoagulants). Always inform your doctor about all medications and supplements.

Q10. Can alcohol be consumed while on DYRONIB 70?
It is best to avoid alcohol, as it may increase liver strain and worsen side effects.

Q11. How long will I need to take DYRONIB 70?
Treatment duration depends on response to therapy. Many patients take it long-term under regular monitoring by their hematologist.

Q12. What monitoring is required while on DYRONIB 70?
Regular blood tests, liver function tests, and heart monitoring are essential to check for side effects and ensure proper dosage.

Q13. Can DYRONIB 70 cause fluid retention?
Yes, it may cause swelling in hands, feet, or around the eyes, and in some cases, fluid around the lungs. Report swelling or shortness of breath promptly.

Q14. What should I do if I miss a dose?
Take the missed dose as soon as you remember. If it is almost time for the next dose, skip the missed dose. Do not double the dose.

Q15. Is DYRONIB 70 effective if previous treatments failed?
Yes, it is specifically designed for patients who are resistant or intolerant to prior tyrosine kinase inhibitors like Imatinib.

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