What is Actilyse 50mg Alteplase 50mg?
Actilyse contains alteplase, a tissue plasminogen activator (tPA). It is a prescription medicine used to dissolve blood clots in certain serious conditions.
What is the use of Actilyse?
Actilyse is used to treat:
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Acute ischemic stroke (to restore blood flow to the brain)
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Acute myocardial infarction (heart attack)
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Pulmonary embolism (clot in the lungs)
It helps break down clots quickly, improving survival and recovery.
Benefits of Actilyse:
✅ Rapid clot dissolution
✅ Restores circulation to affected tissues
✅ Reduces damage during stroke or heart attack
✅ Improves outcomes when given promptly
Side Effects of Actilyse:
Like all medicines, Actilyse can cause side effects. Common and serious ones include:
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Bleeding (internal or external)
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Low blood pressure
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Nausea, vomiting
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Allergic reactions
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Bruising at injection site
Severe bleeding is the most significant risk. Close monitoring in a hospital is required.
Important Information:
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Prescription only – to be administered by trained healthcare professionals.
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Should be given as soon as possible after symptom onset for best results.
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Not suitable for everyone; medical evaluation is essential before use.
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What is Actilyse used for?
Actilyse is used to dissolve blood clots in acute ischemic stroke, heart attack (myocardial infarction), and pulmonary embolism. -
How does Actilyse work?
It activates plasminogen to plasmin, which breaks down fibrin in clots, helping restore blood flow. -
How is Actilyse administered?
It is given as an intravenous infusion by healthcare professionals in a hospital setting. -
How soon should Actilyse be given after stroke symptoms appear?
Ideally within 4.5 hours of stroke symptom onset for maximum effectiveness. -
What are the main benefits of Actilyse 50mg Alteplase 50mg?
Rapid clot breakdown, improved blood flow, reduced tissue damage, and better recovery outcomes. -
What are the common side effects of Actilyse?
Bleeding, low blood pressure, nausea, vomiting, bruising, and in rare cases, allergic reactions. -
Can Actilyse cause severe bleeding?
Yes. Serious bleeding, including intracranial hemorrhage, is a known risk and requires close monitoring. -
Who should not receive Actilyse?
Patients with active bleeding, recent major surgery, severe uncontrolled hypertension, or history of hemorrhagic stroke. -
Is Actilyse the same as a blood thinner?
No. It is a thrombolytic (“clot-busting”) drug, not a blood thinner like heparin or warfarin. -
Can Actilyse be used in children?
It is generally not recommended in pediatric patients except under specialist advice. -
How long does the effect of Actilyse last?
Its clot-dissolving action starts quickly, but bleeding risk can persist for hours after administration. -
Can Actilyse be used in all types of stroke?
No. It is only used for ischemic strokes caused by clots, not for hemorrhagic strokes (bleeding in the brain). -
Does Actilyse require any special monitoring?
Yes. Continuous monitoring of vital signs, neurological status, and bleeding risk is essential. -
What precautions should be taken before using Actilyse?
A brain scan (CT/MRI) is performed to rule out bleeding, and medical history is carefully reviewed. -
Can Actilyse be given with other medications?
Some medicines, like anticoagulants, can increase bleeding risk. Always inform your doctor about all treatments you are taking.
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