Leucovorin Calcium Injection

What is Leucovorin Calcium Injection?

Leucovorin Calcium Injection is a medication that contains folinic acid, a form of vitamin B9. It is commonly used to prevent or treat the harmful effects of certain chemotherapy drugs, especially methotrexate, and to enhance the effectiveness of others like fluorouracil.

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What is the Use of Leucovorin Calcium Injection?

Leucovorin Calcium Injection is used in combination with chemotherapy to:

• Reduce the toxic effects of methotrexate.

• Increase the effectiveness of 5-fluorouracil (5-FU) in treating cancers.

• Treat certain types of anemia caused by folic acid deficiency.

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Benefits of Leucovorin Calcium Injection

• Protects healthy cells during chemotherapy.

• Improves the cancer-fighting effectiveness of certain drugs.

• Helps in faster recovery from chemotherapy side effects.

• Supports the treatment of megaloblastic anemia.

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Side Effects of Leucovorin Calcium Injection

Common side effects may include:

• Nausea or vomiting

• Allergic reactions (rash, itching)

• Diarrhea

• Dizziness or headache

Severe reactions are rare but should be reported to a doctor immediately.

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Disclaimer

The information provided here is for educational purposes only and should not replace medical advice. Always consult your doctor or pharmacist before using Leucovorin Calcium Injection.

Frequently Asked Questions: 

1. What is Leucovorin Calcium Injection?

Leucovorin Calcium Injection is a folinic acid formulation used to reduce the toxic effects of chemotherapy drugs like methotrexate and enhance the action of fluorouracil in cancer treatment.

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2. What is the use of Leucovorin Calcium Injection?

It is used as rescue therapy after high-dose methotrexate, in combination with fluorouracil for colorectal cancer, and to treat folate deficiency-related anemia.

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3. How does Leucovorin Calcium Injection work?

Leucovorin supplies the body with active folate, helping healthy cells recover from chemotherapy while improving the effectiveness of certain anticancer drugs.

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4. What are the benefits of Leucovorin Calcium Injection?

It protects normal cells from methotrexate toxicity, enhances the cancer-fighting ability of fluorouracil, and helps correct folate deficiencies.

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5. What are the side effects of Leucovorin Calcium Injection?

Common side effects include nausea, vomiting, diarrhea, allergic reactions, and mild fever. Always consult your doctor for proper medical guidance.

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6. How is Leucovorin Calcium Injection administered?

It is given by intravenous (IV) or intramuscular (IM) injection under the supervision of a qualified healthcare professional.

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7. Can Leucovorin Calcium Injection be used with methotrexate?

Yes, it is used with methotrexate as a rescue therapy to prevent or minimize toxic side effects caused by methotrexate treatment.

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8. What precautions should be taken while using Leucovorin Calcium Injection?

Inform your doctor about allergies, ongoing treatments, or vitamin supplements before use. It should always be used under medical supervision.

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9. Is Leucovorin Calcium Injection safe during pregnancy?

Leucovorin should only be used during pregnancy if clearly needed and prescribed by a doctor after assessing risks and benefits.

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10. Who manufactures and exports Leucovorin Calcium Injection from India?

Several WHO-GMP and ISO-certified pharmaceutical companies in India manufacture and export high-quality Leucovorin Calcium Injection globally, including to the USA, UK, Africa, and Gulf countries.