ESTRIOL CREAM

What is Estriol Cream?

Estriol Cream is a topical medication that contains estriol, a naturally occurring estrogen hormone. It is primarily used to treat symptoms of vaginal atrophy and other menopausal-related conditions in women caused by low estrogen levels. Estriol is a milder form of estrogen compared to other types (like estradiol), making it a preferred choice for localized hormone therapy with fewer systemic effects.

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What is the Use of Estriol Cream?

Estriol Cream is commonly prescribed for:

• Vaginal dryness

• Itching or irritation in the vaginal area

• Painful intercourse (dyspareunia)

• Urinary discomfort or frequent infections

• Mild urinary incontinence

• Support during perimenopause and postmenopause

• Occasionally used in hormone replacement therapy (HRT)

It is applied intravaginally or externally as directed by a healthcare provider.

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Benefits of Estriol Cream

• Restores vaginal health by replenishing moisture and elasticity

• Reduces itching, burning, and dryness

• Improves sexual comfort and decreases pain during intercourse

• Supports urinary tract health by reducing infection risks

• Helps maintain vaginal pH and healthy flora

• Milder estrogen reduces risk of systemic hormonal side effects

• Useful in long-term menopause care with a low risk profile

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How to Use Estriol Cream

• Use exactly as prescribed by your doctor

• Typically applied once daily for initial treatment, then reduced to 2–3 times per week for maintenance

• Wash hands before and after application

• Use the applicator provided for intravaginal use

• Follow instructions carefully to avoid overuse or underuse

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Side Effects of Estriol Cream

While Estriol Cream is generally well-tolerated, some users may experience side effects such as:

Common Side Effects:

• Vaginal irritation or discharge

• Mild abdominal cramps

• Breast tenderness

• Headache

Rare or Serious Side Effects (seek medical attention):

• Vaginal bleeding

• Blood clots

• Allergic reactions (rash, itching, swelling)

• Mood changes or migraines

• Breast lumps

Always consult your healthcare provider if you experience any unusual symptoms.

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Precautions & Warnings

• Not for use in women with breast cancer, undiagnosed vaginal bleeding, or a history of blood clots

• Should not be used during pregnancy or breastfeeding

• Long-term use should be regularly monitored by a physician

• Discuss any other medications or health conditions before starting therapy

1. What is Estriol Cream used for?
   Estriol Cream is primarily used to treat symptoms of vaginal atrophy, such as dryness, itching, burning, and painful intercourse caused by low estrogen levels, especially during menopause.

2. How does Estriol Cream work?
   It works by delivering estriol, a form of estrogen, directly to the vaginal tissues, helping to restore moisture, elasticity, and normal function of the vaginal and urinary areas.

3. Is Estriol Cream safe to use?
   Yes, when used as directed by a healthcare provider, Estriol Cream is generally considered safe and well-tolerated, especially due to its low systemic absorption.

4. How should I apply Estriol Cream?
   Estriol Cream is applied intravaginally or externally, usually once daily for a few weeks and then reduced to a maintenance dose of 2–3 times per week. Always follow your doctor’s instructions.

5. Can Estriol Cream be used long term?
   Yes, many women use Estriol Cream long-term under medical supervision. Regular check-ups are recommended to monitor hormone levels and any side effects.

6. What are the common side effects of Estriol Cream?
   Common side effects include vaginal irritation, discharge, breast tenderness, or mild cramps. Most side effects are mild and temporary.

7. Can I use Estriol Cream during pregnancy or breastfeeding?
   No, Estriol Cream should not be used during pregnancy or while breastfeeding unless specifically directed by a healthcare provider.

8. Is Estriol Cream a form of hormone replacement therapy (HRT)?
   Yes, it is considered a localized form of hormone replacement therapy, with minimal impact on the rest of the body compared to systemic HRT.

9. How quickly does Estriol Cream start working?
   Many women notice symptom relief within a few days to a few weeks of consistent use.

10. Can Estriol Cream prevent urinary tract infections (UTIs)?
    By improving vaginal and urethral health, Estriol Cream may reduce the risk of recurrent UTIs, particularly in postmenopausal women.

11. Can Estriol Cream be used with other vaginal products?
    It’s best to consult your doctor before using other vaginal products (like lubricants or antifungals) alongside Estriol Cream to avoid interactions.

12. Does Estriol Cream affect fertility?
    Estriol Cream is typically not used in women who are trying to conceive and may affect natural hormonal balance, so fertility could be temporarily altered.

13. Will Estriol Cream cause weight gain?
    Estriol Cream has minimal systemic absorption, so it is unlikely to cause weight gain when used as prescribed.

14. Do I need a prescription to buy Estriol Cream?
    Yes, in most countries, Estriol Cream is available by prescription only and should be used under medical supervision.

15. What should I do if I miss a dose?
    If you miss a dose, apply it as soon as you remember. If it’s almost time for your next dose, skip the missed dose—do not double up.