Tryprine 300mgTrientine Capsules

What is Tryprine 300mgTrientine Capsules?

Tryprine 300mgTrientine Capsules is a chelating agent medicine containing Trientine as its active ingredient. It is primarily used to remove excess copper from the body in patients with Wilson’s disease, a genetic disorder where copper accumulates in the liver, brain, and other organs. Trientine binds to copper and helps eliminate it through urine.

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What is the Use of Tryprine 300mgTrientine Capsules?

Tryprine is prescribed for:

• Treatment of Wilson’s disease when penicillamine (another chelating agent) is not suitable or has caused intolerance.

• Reducing high copper levels in the body to prevent damage to the liver, nervous system, and other tissues.

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Benefits of Tryprine Capsules

✅ Effective Copper Removal: Binds excess copper and promotes its excretion.
✅ Alternative to Penicillamine: Suitable for patients intolerant to penicillamine.
✅ Helps Protect Organs: Reduces copper-related damage to the liver and brain.
✅ Oral Therapy: Convenient capsule form for easy administration.

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How to Use Tryprine 300mgTrientine Capsules?

• Take the capsule by mouth on an empty stomach, at least 1 hour before or 2 hours after meals.

• Swallow whole with a glass of water.

• Take exactly as prescribed by your doctor—usually 2–4 times daily.

• Do not adjust or stop the dose without consulting your healthcare provider.

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Side Effects of Tryprine Capsules

Like all medications, Tryprine can cause side effects.
Common side effects include:

• Nausea or vomiting

• Abdominal discomfort

• Mild anemia (low red blood cells)

• Skin rash

• Mild protein loss in urine

Serious side effects (rare):

• Severe anemia or low white blood cell count

• Severe allergic reactions

• Worsening of neurological symptoms

Important: If you experience unusual fatigue, severe infections, bruising, or swelling, seek medical help immediately.

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Precautions and Warnings

• Regular blood counts and urine tests are needed to monitor safety.

• Avoid iron supplements or take them at least 2 hours apart, as iron can interfere with absorption.

• Use with caution in pregnancy—consult your doctor for risks and benefits.

• Keep out of reach of children

1. What is Tryprine 300mgTrientine Capsules used for?
   It is used to treat Wilson’s disease, a condition where copper builds up in the body and damages organs such as the liver and brain.

2. How does Tryprine work?
   Tryprine contains Trientine, a chelating agent that binds to excess copper and helps remove it through urine.

3. How should I take Tryprine Capsules?
   Take it by mouth on an empty stomach, at least 1 hour before or 2 hours after meals, exactly as prescribed by your doctor.

4. Can Tryprine be taken with food?
   No. Food significantly reduces absorption. Always take it on an empty stomach.

5. What should I do if I miss a dose?
   Take the missed dose as soon as you remember. If it’s almost time for the next dose, skip the missed one. Do not double the dose.

6. Are there any common side effects?
   Yes. Some common side effects include:

   • Nausea

   • Stomach discomfort

   • Mild anemia

   • Skin rash

7. Does Tryprine affect blood counts?
   Yes. It can lower red or white blood cells. Your doctor will monitor your blood regularly.

8. How long do I need to take Tryprine?
   Wilson’s disease requires lifelong treatment. Do not stop therapy without your doctor’s advice.

9. Can I take iron supplements while on Tryprine?
   Iron binds with Trientine and reduces its effectiveness. If you must take iron, space it at least 2 hours apart.

10. Is Tryprine safe during pregnancy?
    Discuss risks and benefits with your doctor. Copper control remains important during pregnancy, but dosing may need adjustment.

11. Does Tryprine interact with other medicines?
    Yes. It may interact with:

• Iron supplements

• Zinc preparations

• Other chelators
  Always inform your doctor about all medicines you take.

12. What tests will I need while taking Tryprine?
    Regular monitoring of:

• Blood counts

• Liver function

• Urinary copper levels

13. Can Tryprine make neurological symptoms worse?
    In some cases, symptoms may temporarily worsen when starting treatment. Contact your doctor if this happens.

14. How should I store Tryprine Capsules?
    Store in a cool, dry place below 25°C, away from children and moisture.

15. Can children use Tryprine?
    Yes. It can be used in children under specialist supervision, with carefully adjusted dosing.