What is Mabura Adalimumab 40mg PFS Injection ?
Mabura Adalimumab Injection contains adalimumab, a type of medicine known as a TNF inhibitor (Tumor Necrosis Factor blocker).
It is a monoclonal antibody, produced by recombinant DNA technology, that binds to TNF-alpha, a protein involved in inflammation. By blocking TNF-alpha, Mabura helps control inflammatory diseases.
This injection comes as a pre-filled syringe (PFS) containing 40 mg of adalimumab for subcutaneous injection.
What is the use of Mabura Adalimumab 40mg PFS Injection?
Mabura Adalimumab is used to treat autoimmune and inflammatory conditions, including:
✅ Rheumatoid Arthritis (moderate to severe)
✅ Psoriatic Arthritis
✅ Ankylosing Spondylitis
✅ Crohn’s Disease (moderate to severe)
✅ Ulcerative Colitis
✅ Plaque Psoriasis (chronic severe)
✅ Hidradenitis Suppurativa
✅ Juvenile Idiopathic Arthritis
Your doctor will decide the exact indication and dosing schedule based on your condition.
Benefits of Mabura Adalimumab 40mg PFS Injection
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Reduces inflammation and pain: Helps relieve swelling, stiffness, and discomfort.
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Slows disease progression: Can prevent joint damage and disability in arthritis.
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Improves daily function: Enhances mobility and quality of life.
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Convenient dosing: Usually administered once every 2 weeks.
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Self-administration: Pre-filled syringe allows patients or caregivers to inject at home after proper training.
How should Mabura Adalimumab 40mg PFS Injection?
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Administered subcutaneously (under the skin), usually into the thigh or abdomen.
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Do not inject into areas that are red, tender, bruised, or hard.
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Dosage and frequency depend on the condition being treated.
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Your healthcare provider will train you on proper injection technique.
Side Effects of Mabura Adalimumab 40mg PFS Injection
Like all biologic therapies, Mabura can cause side effects.
Common side effects:
✅ Injection site reactions (pain, redness, itching)
✅ Headache
✅ Nausea
✅ Respiratory infections (sinusitis, sore throat)
Serious side effects (seek medical help):
❗ Serious infections (tuberculosis, fungal infections, sepsis)
❗ Reactivation of hepatitis B
❗ Heart failure worsening
❗ Nervous system problems (multiple sclerosis, seizures)
❗ Blood disorders (low blood counts)
❗ Certain cancers (lymphomas, skin cancer) (rare)
Precautions and Warnings
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Infections: You must be screened for tuberculosis and hepatitis B before starting.
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Vaccinations: Avoid live vaccines during treatment.
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Pregnancy & Breastfeeding: Use only if clearly needed; discuss risks with your doctor.
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Monitoring: Regular blood tests may be needed to watch for infections and blood count changes.
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Do not use if: You have active severe infections or untreated TB.
Storage Information
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Store in the refrigerator (2–8°C).
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Do not freeze.
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Keep in the original carton to protect from light.
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If needed, it may be kept at room temperature (up to 25°C) for a maximum of 14 days, after which it must be discarded if not used.
✅ 1. What is Mabura Adalimumab 40mg PFS Injection used for?
It treats autoimmune conditions such as rheumatoid arthritis, ankylosing spondylitis, psoriatic arthritis, plaque psoriasis, Crohn’s disease, and ulcerative colitis.
✅ 2. How does Mabura Adalimumab work?
It is a TNF (tumor necrosis factor) inhibitor that reduces inflammation by blocking TNF-alpha, a substance in the body that causes inflammation.
✅ 3. How is Mabura Adalimumab administered?
It is given as a subcutaneous (under the skin) injection, usually in the thigh or abdomen.
✅ 4. How often do I need to take this injection?
The dosing schedule varies by disease but is typically every 2 weeks. Your doctor will give you a personalized regimen.
✅ 5. Can I inject Mabura Adalimumab by myself?
Yes. After proper training from a healthcare professional, many patients self-inject at home.
✅ 6. What are the common side effects?
Injection site reactions (pain, redness, swelling), headache, rash, and respiratory infections are common.
✅ 7. Are there serious risks with this medicine?
Yes. It can increase the risk of serious infections (e.g., TB, fungal infections), certain cancers, and allergic reactions.
✅ 8. Do I need any tests before starting treatment?
Yes. TB screening, hepatitis B tests, and sometimes blood counts are required before starting therapy.
✅ 9. Can I take vaccines while on Mabura Adalimumab?
You should avoid live vaccines. Inactivated vaccines are usually safe but always consult your doctor first.
✅ 10. Can pregnant or breastfeeding women use this injection?
Use during pregnancy and breastfeeding should be only if clearly needed and prescribed by your doctor.
✅ 11. What should I do if I miss a dose?
Take the missed dose as soon as you remember. Then continue your regular schedule. Never double up doses.
✅ 12. Can Mabura Adalimumab be used with other medications?
Yes, but caution is needed. It can be used with methotrexate and other DMARDs. Always tell your doctor about all medicines you take.
✅ 13. How should I store the injection?
Store in the refrigerator (2–8°C). Do not freeze. Keep in the original carton to protect from light.
✅ 14. Is there any special precaution during travel?
Use a cool pack to maintain the recommended temperature if you are traveling.
✅ 15. When will I start to feel better?
Some patients see improvement within a few weeks, but it may take several months for full benefit.
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