What is HEPCINAT 400MG?
HEPCINAT 400MG is a prescription antiviral medication containing Sofosbuvir 400 mg as its active ingredient. It is manufactured by Natco Pharma Ltd. and belongs to a class of medicines known as direct-acting antivirals (DAAs). This medication is used in the treatment of chronic Hepatitis C virus (HCV) infection, a condition that affects the liver. HEPCINAT 400MG works by reducing the amount of hepatitis C virus in the body, helping the immune system fight the infection and improving liver health.
What is the use of HEPCINAT 400MG?
HEPCINAT 400MG is primarily used for:
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The treatment of chronic Hepatitis C infection in adults.
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It is often prescribed in combination with other antiviral agents such as Ledipasvir, Daclatasvir, or Velpatasvir depending on the type (genotype) of HCV infection.
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It helps prevent complications such as liver cirrhosis, liver failure, and liver cancer by effectively lowering viral load.
Benefits of HEPCINAT 400MG
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High Cure Rate: Proven to achieve a sustained virologic response (SVR) in most patients.
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Improves Liver Function: Gradually reduces liver inflammation and damage.
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Well-Tolerated: Minimal side effects compared to older Hepatitis C treatments.
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Oral Convenience: Easy-to-take once-daily oral tablet.
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Safe Combination Therapy: Works effectively when used with other DAAs for complete viral clearance.
How to Use HEPCINAT 400MG
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Take one tablet (400 mg) orally once daily with or without food, or as directed by your physician.
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Always follow your doctor’s dosage schedule and do not skip or double doses.
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The duration of treatment usually ranges from 12 to 24 weeks, depending on the patient’s condition and medical history.
Possible Side Effects of HEPCINAT 400MG
While HEPCINAT 400MG is generally well-tolerated, some patients may experience mild side effects such as:
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Headache
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Fatigue or tiredness
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Nausea
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Insomnia (trouble sleeping)
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Mild irritability
Serious side effects are rare but may include:
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Slow or irregular heartbeat (when combined with Amiodarone)
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Allergic reactions like rash, itching, or swelling
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Shortness of breath or chest discomfort
If you experience any severe reactions, seek medical attention immediately.
Precautions and Warnings
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Consult your doctor if you have kidney or liver problems before starting the medicine.
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Avoid alcohol consumption during treatment.
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Not recommended for use during pregnancy or breastfeeding unless advised by a healthcare provider.
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Do not stop the medication without consulting your doctor to prevent relapse of infection.
1. What is the main ingredient in HEPCINAT 400MG?
The active ingredient is Sofosbuvir 400mg, an antiviral agent that targets the Hepatitis C virus.
2. What is HEPCINAT 400MG used for?
It is used for treating chronic Hepatitis C virus infection in adults.
3. How does HEPCINAT 400MG work?
It inhibits an enzyme (NS5B RNA polymerase) that the Hepatitis C virus needs to replicate, thereby reducing viral multiplication.
4. Can HEPCINAT 400MG cure Hepatitis C completely?
Yes, when used with other antiviral drugs as prescribed, it can completely cure Hepatitis C in most cases.
5. How long does the HEPCINAT treatment last?
Typically, treatment lasts 12 to 24 weeks, depending on the type of Hepatitis C and patient response.
6. Can I take HEPCINAT 400MG on an empty stomach?
Yes, it can be taken with or without food.
7. What should I do if I miss a dose?
Take the missed dose as soon as you remember. If it’s almost time for your next dose, skip it — do not double up.
8. Is HEPCINAT 400MG safe?
Yes, it is generally safe and well-tolerated when taken under medical supervision.
9. Can HEPCINAT 400MG be used alone?
No. It must be used in combination with other antiviral agents like Daclatasvir, Ledipasvir, or Velpatasvir.
10. Who should not take HEPCINAT 400MG?
Patients allergic to Sofosbuvir or any tablet component, and those with severe heart problems or advanced kidney disease, should avoid it unless approved by a doctor.
11. Can pregnant women take HEPCINAT 400MG?
It is not recommended during pregnancy unless specifically prescribed by a healthcare professional.
12. Can I drink alcohol while on HEPCINAT 400MG?
Avoid alcohol, as it can increase liver damage and reduce treatment effectiveness.
13. What happens if I overdose on HEPCINAT 400MG?
Seek immediate medical attention. Symptoms may include nausea, dizziness, or fatigue.
14. Does HEPCINAT 400MG interact with other drugs?
Yes, it can interact with Amiodarone, Rifampin, St. John’s Wort, and certain anti-seizure medications. Always inform your doctor of all ongoing medicines.
15. How should HEPCINAT 400MG be stored?
Keep it in a cool, dry place below 30°C, away from light and moisture.






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