ELEFTHA 440MG

Product Name: ELEFTHA 440MG
Salt Name: Trastuzumab
Strength: 440 mg (Lyophilized powder for IV infusion)
Manufacturer: Intas Pharmaceuticals Ltd.
Storage: Store in a refrigerator at 2°C–8°C. Do not freeze. Protect from light.
Presentation: Single-use vial containing 440 mg Trastuzumab with sterile water for injection (diluent) for IV infusion.

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What is ELEFTHA 440MG?

ELEFTHA 440MG is an anticancer medicine that contains Trastuzumab 440 mg as its active ingredient. Trastuzumab is a monoclonal antibody used in targeted cancer therapy. It specifically binds to the HER2 receptor, a protein found in some types of cancer cells, and blocks their growth. ELEFTHA is usually administered by intravenous (IV) infusion under medical supervision.


What is the use of ELEFTHA 440MG?

ELEFTHA 440MG is used in the treatment of cancers that overexpress the HER2 protein, including:

  • Breast cancer (HER2-positive)

  • Metastatic breast cancer

  • Gastric (stomach) cancer – HER2-positive advanced gastric adenocarcinoma


Benefits of ELEFTHA 440MG:

  • Targets and blocks HER2-positive cancer cells specifically, reducing harm to normal cells.

  • Improves survival rates and disease-free progression in HER2-positive breast and gastric cancer patients.

  • Can be used alone or in combination with other chemotherapy agents for greater effectiveness.

  • Reduces the risk of cancer recurrence after surgery in early-stage HER2-positive breast cancer.


Side Effects of ELEFTHA 440MG:

Like all cancer medicines, ELEFTHA may cause side effects. Some are mild, while others may require medical attention:

  • Common side effects:

    • Fever, chills, headache, nausea

    • Diarrhea, fatigue, weakness

    • Rash, infusion-related reactions

    • Low white blood cell count (risk of infection)

  • Serious side effects:

    • Heart problems (congestive heart failure, reduced heart pumping ability)

    • Severe infusion reactions (shortness of breath, chest pain, swelling)

    • Lung problems (inflammation, breathing difficulties)

    • Severe allergic reactions

Q1. What is ELEFTHA 440MG used for?
ELEFTHA 440MG is used to treat HER2-positive breast cancer (early and metastatic) and HER2-positive gastric cancer.

Q2. What is the active ingredient in ELEFTHA 440MG?
It contains Trastuzumab 440 mg, a monoclonal antibody that targets the HER2 protein on cancer cells.

Q3. How does ELEFTHA 440MG work?
It attaches to the HER2 receptor on cancer cells, blocking their growth signals and helping the immune system destroy them.

Q4. How is ELEFTHA 440MG given?
It is given by intravenous (IV) infusion in a hospital, usually under the supervision of an oncologist.

Q5. How long does treatment with ELEFTHA 440MG last?
The duration depends on cancer type and stage. For early breast cancer, it is often given for 1 year. For advanced cancers, it may continue as long as it is effective.

Q6. Can ELEFTHA 440MG be used with other chemotherapy drugs?
Yes, it is often used in combination with medicines like Paclitaxel, Docetaxel, Cisplatin, or Capecitabine for better results.

Q7. What tests are required before taking ELEFTHA 440MG?
A HER2 test is required to confirm HER2-positive cancer. Heart tests (like Echocardiogram or MUGA scan) are also done before and during treatment.

Q8. What are the common side effects of ELEFTHA 440MG?
Fever, chills, weakness, nausea, diarrhea, infusion-related reactions, and low blood counts.

Q9. Can ELEFTHA 440MG affect the heart?
Yes. It may cause heart problems such as reduced heart pumping function or heart failure. Regular heart monitoring is needed.

Q10. Is ELEFTHA 440MG safe during pregnancy?
No. Trastuzumab can harm the unborn baby. Women must use effective contraception during treatment and for at least 7 months after the last dose.

Q11. Can breastfeeding mothers use ELEFTHA 440MG?
No. Breastfeeding should be avoided during treatment and for 7 months after the last dose.

Q12. What should I do if I miss a dose?
Inform your oncologist immediately. They will reschedule the infusion as soon as possible. Do not self-adjust doses.

Q13. Can men also take ELEFTHA 440MG?
Yes. It is also prescribed for men with HER2-positive breast cancer or gastric cancer.

Q14. Are there any serious infusion reactions?
Yes. Some patients may experience difficulty breathing, chest pain, or severe allergic reactions during infusion. The doctor may slow or stop the infusion if this happens.

Q15. How should ELEFTHA 440MG be stored?
It must be stored in a refrigerator (2°C–8°C). It should not be frozen and must be kept away from light.

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