DOXOREX PL 50MG INJ

What is DOXOREX PL 50MG Injection?

DOXOREX PL 50MG Injection is an anticancer (chemotherapy) medicine that contains Doxorubicin Hydrochloride (Pegylated Liposomal) 50 mg as its active ingredient. It belongs to the class of anthracycline antibiotics used in cancer treatment. The liposomal formulation allows slower release and longer circulation in the body, improving effectiveness and reducing toxicity compared to conventional doxorubicin.

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What is the use of DOXOREX PL 50MG Injection?

It is used in the treatment of several types of cancer, including:

• Breast cancer

• Ovarian cancer

• Multiple myeloma (in combination with other drugs)

• Kaposi’s sarcoma in HIV-positive patients

• May also be used in other solid tumors as prescribed by the oncologist.

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Benefits of DOXOREX PL 50MG Injection:

• More targeted delivery due to liposomal formulation, leading to reduced damage to healthy tissues.

• Lower risk of heart toxicity compared to conventional doxorubicin.

• Provides effective tumor shrinkage and improved survival in certain cancers.

• Can be used as a single agent or in combination with other chemotherapy medicines.

• Suitable for patients who cannot tolerate conventional doxorubicin due to cardiac risk.

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Side Effects of DOXOREX PL 50MG Injection:

Like other chemotherapy drugs, DOXOREX PL 50MG Injection may cause side effects:

• Common side effects:

  • Fatigue, nausea, vomiting

  • Loss of appetite

  • Hair thinning or hair loss

  • Mouth sores (stomatitis)

  • Low blood cell counts (infections, anemia, easy bruising)

  • Red urine for a few days after injection (normal effect)

• Specific side effect (unique to liposomal doxorubicin):

  • Hand-Foot Syndrome (Palmar-Plantar Erythrodysesthesia): redness, pain, or peeling of palms and soles.

• Serious side effects (seek immediate care):

  • Severe allergic reaction (swelling, breathing difficulty)

  • Heart problems (irregular heartbeat, chest pain)

  • Severe infection due to low white blood cell count

Q1. What is DOXOREX PL 50MG Injection used for?
It is used in the treatment of breast cancer, ovarian cancer, multiple myeloma, and AIDS-related Kaposi’s sarcoma.

Q2. How does DOXOREX PL 50MG Injection work?
It contains pegylated liposomal doxorubicin, which enters cancer cells, damages their DNA, and prevents them from growing and dividing.

Q3. What is the difference between DOXOREX PL and regular doxorubicin?
The liposomal form allows slower release, longer circulation, and less heart toxicity, making it safer for patients who cannot tolerate standard doxorubicin.

Q4. How is DOXOREX PL 50MG given?
It is administered as an intravenous (IV) infusion in a hospital or chemotherapy center by a trained healthcare professional.

Q5. How often will I receive DOXOREX PL 50MG?
The schedule depends on your cancer type and treatment plan, usually once every few weeks, as prescribed by your oncologist.

Q6. What are the common side effects of DOXOREX PL 50MG?
Nausea, vomiting, fatigue, mouth sores, hair loss, low blood counts, and red urine for a short time after injection.

Q7. What is Hand-Foot Syndrome in DOXOREX PL treatment?
It’s a unique side effect where the palms and soles may become red, painful, or peel. Cooling measures and creams can help relieve symptoms.

Q8. Does DOXOREX PL 50MG cause hair loss?
Yes, hair thinning or loss is common, but it is usually temporary, and hair regrows after treatment.

Q9. Can DOXOREX PL 50MG affect my heart?
Although it is safer than conventional doxorubicin, heart monitoring (echocardiogram/ECG) is needed, especially with long-term use.

Q10. Can pregnant or breastfeeding women use DOXOREX PL 50MG?
No. It can harm the unborn baby and should not be used in pregnancy or while breastfeeding. Effective contraception is advised.

Q11. Can I take other medicines with DOXOREX PL 50MG?
Some medicines may interact with chemotherapy. Always inform your doctor about all prescriptions, supplements, or herbal products you are taking.

Q12. What precautions should I take during treatment?

• Avoid infections (practice good hygiene, avoid crowded places).

• Stay well hydrated.

• Report any unusual bleeding, chest pain, or fever immediately.

Q13. Can I drink alcohol while on DOXOREX PL 50MG?
It’s best to avoid alcohol, as it may worsen liver strain and increase treatment side effects.

Q14. How long will I need DOXOREX PL treatment?
The duration depends on your cancer type, response to therapy, and doctor’s plan. It is often part of a long-term chemotherapy regimen.

Q15. How should DOXOREX PL 50MG be stored?
Unopened vials should be stored at 2–8°C (refrigerated), protected from light. Hospital staff handle storage and preparation.