COLSTIM 300MG PFS

What is COLSTIM 300MG PFS?

COLSTIM 300MG PFS is a filgrastim-based injection (Granulocyte Colony-Stimulating Factor – G-CSF) available in a pre-filled syringe (PFS) formulation. It is used to stimulate the production of white blood cells (neutrophils) in patients whose levels are low due to chemotherapy, bone marrow transplant, or certain medical conditions.

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What is the use of COLSTIM 300MG PFS?

• Helps manage neutropenia (low neutrophil count) caused by chemotherapy or radiation therapy.

• Supports faster recovery of the immune system after bone marrow or stem cell transplantation.

• Used in patients with severe chronic neutropenia due to congenital, cyclic, or idiopathic causes.

• Aids in mobilizing stem cells into the bloodstream for collection before a stem cell transplant.

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Benefits of COLSTIM 300MG PFS

• Reduces the risk of serious infections in patients undergoing chemotherapy.

• Enhances immune recovery, helping patients resume cancer treatment without delays.

• Convenient pre-filled syringe form ensures accurate dosing and easy administration.

• Improves overall quality of life by lowering hospitalization and infection-related complications.

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Side Effects of COLSTIM 300MG PFS

Like all medicines, COLSTIM 300MG PFS may cause some side effects. Common and possible ones include:

• Bone pain or muscle pain

• Injection site redness or swelling

• Headache, fatigue, or fever

• Nausea or diarrhea

Serious but rare side effects:

• Allergic reactions (rash, breathing difficulty, swelling)

• Enlarged spleen (pain in left upper abdomen or shoulder tip)

• Lung problems (shortness of breath, cough)

1. What is COLSTIM 300MG PFS used for?

It is used to treat or prevent neutropenia (low white blood cell count) caused by chemotherapy, radiation, bone marrow transplant, or certain medical conditions.

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2. What is the active ingredient in COLSTIM 300MG PFS?

The active ingredient is Filgrastim, a granulocyte colony-stimulating factor (G-CSF).

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3. How does COLSTIM 300MG PFS work?

It stimulates the bone marrow to produce more neutrophils, which helps fight infections.

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4. How is COLSTIM 300MG PFS given?

It is administered as a subcutaneous injection (under the skin) or sometimes intravenously, usually under the supervision of a healthcare professional.

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5. Can COLSTIM 300MG PFS be self-administered?

Yes, in some cases doctors may train patients or caregivers to inject it at home using the pre-filled syringe.

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6. What are the common side effects of COLSTIM 300MG PFS?

Bone pain, muscle pain, headache, injection site redness, fever, nausea, and fatigue are common.

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7. Are there any serious side effects to watch for?

Yes. Rare but serious side effects include:

• Enlarged spleen (pain in left upper abdomen/shoulder tip)

• Breathing difficulty, cough, or chest pain

• Severe allergic reactions

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8. How long does it take for COLSTIM 300MG PFS to work?

Most patients see an increase in white blood cells within 1–2 days after starting treatment.

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9. What should I do if I miss a dose?

Contact your doctor immediately. Do not take a double dose without medical advice.

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10. Can COLSTIM 300MG PFS be used during pregnancy or breastfeeding?

It should only be used if clearly needed and prescribed by a doctor. Safety during pregnancy and breastfeeding is not fully established.

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11. Can COLSTIM 300MG PFS interact with other medicines?

Yes. Always inform your doctor about any medicines, chemotherapy drugs, or supplements you are taking.

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12. How should COLSTIM 300MG PFS be stored?

• Store in a refrigerator (2°C–8°C)

• Do not freeze

• Keep in the original carton to protect from light

• Do not shake the syringe

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13. Can children use COLSTIM 300MG PFS?

Yes, it can be prescribed for children with severe chronic neutropenia or other conditions, but only under strict medical supervision.

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14. How long will I need to take COLSTIM 300MG PFS?

The duration depends on your medical condition and treatment plan. Some patients take it for a few days after chemotherapy, while others may need longer courses.

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15. What precautions should I take while using COLSTIM 300MG PFS?

• Report any unusual pain in the left upper abdomen or chest

• Monitor for fever and infections

• Do not use the syringe if it looks cloudy or discolored